Neem is an extract of leaves and bark of an Asian tree, Azadirachta indica, and is considered one of the principal remedies in Ayurvedic medicine. Traditionally, neem is used to treat parasites, bacterial, fungal, viral infections, and various skin diseases. In addition, neem is used as an herbal contraceptive, sedative and as a remedy to treat diabetes and cancer. The known active constituents of neem extract include nimbin, azadirachtin, nimbidiol, quercetin and nimbidin, among others. Experimental data indicate that neem components inhibit poliovirus and herpes viruses, possesses bactericidal activity toward gram positive and gram negative bacteria, fungi and parasites. It also stimulates TH1-dependent immune responses, inhibits growth of cancer cells, stimulates utilization of glucose, and inhibits growth of new blood vessels (neoangiogenes).
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