Agaricus blazei is an edible mushroom native to Brazil and is cultivated in Japan for medicinal uses. May be used for lipid control, lowering blood glucose level, improving natural killer cell activity, and increasing blood vessel elasticity.

Antrodia camphorata, a native Taiwanese mushroom, possesses strong antioxidant activity, inhibits thickening of blood vessel walls, and promotes vasodilation.

Piperine included to enhance absorption.